Spinal Manipulation, Medication, or Home Exercise With Advice for Acute and Subacute Neck Pain

Gert Bronfort, DC, PhD; Roni Evans, DC, MS; Alfred V. Anderson, DC, MD; Kenneth H. Svendsen, MS; Yiscah Bracha, MS; Richard H. Grimm, MD, MPH, PhD

From Northwestern Health Sciences University, Pain Management and Rehabilitation Center, and Berman Center for Outcomes and Clinical Research at the Minneapolis Medical Research Foundation, Minneapolis, Minnesota.

Acknowledgment: The authors thank the study staff for dedicating substantial time and energy to ensure successful completion of the trial, as well as Brent Leininger, DC, and Jennifer Hart, MS, for their technical assistance in preparing this manuscript.

Grant Support: By the National Institutes of Health's National Center for Complementary and Alternative Medicine (grant R01 AT000707).

Reproducible Research Statement:Study protocol and statistical code: Available from Dr. Bronfort (e-mail, gbronfort@nwhealth.edu). Data set: Not available.

Corresponding Author: Gert Bronfort, DC, PhD, Wolfe-Harris Center for Clinical Studies, Northwestern Health Sciences University, 2501 West 84th Street, Bloomington, MN 55431; e-mail, gbronfort@nwhealth.edu.

Current Author Addresses: Drs. Bronfort and Evans: Wolfe-Harris Center for Clinical Studies, Northwestern Health Sciences University, 2501 West 84th Street, Bloomington, MN 55431.

Dr. Anderson: Medical Pain Management, 5775 Wayzata Boulevard, Suite 110, St. Louis Park, MN 55416.

Mr. Svendsen: 900 Forest Avenue, Birmingham, MI 48009.

Mr. Bracha: Division of Health Policy and Clinical Effectiveness, Cincinnati Children's Hospital, 3333 Burnet Avenue, MLC 5040, Cincinnati, OH 45229.

Dr. Grimm: Berman Center for Outcomes and Clinical Research, 825 South 8th Street, Suite 440, Minneapolis, MN 55404.

Author Contributions: Conception and design: G. Bronfort, R. Evans, R.H. Grimm.

Analysis and interpretation of the data: G. Bronfort, R. Evans, K.H. Svendsen, Y. Bracha, R.H. Grimm.

Drafting of the article: G. Bronfort, R. Evans, Y. Bracha, R.H. Grimm.

Critical revision of the article for important intellectual content: G. Bronfort, R. Evans, Y. Bracha, R.H. Grimm.

Final approval of the article: G. Bronfort, R. Evans, A.V. Anderson, Y. Bracha, R.H. Grimm.

Provision of study materials or patients: A.V. Anderson.

Statistical expertise: G. Bronfort, K.H. Svendsen, Y. Bracha, R.H. Grimm.

Obtaining of funding: G. Bronfort, R. Evans, R.H. Grimm.

Administrative, technical, or logistic support: G. Bronfort, R. Evans.

Collection and assembly of data: R. Evans, A.V. Anderson.