Letters
4 February 2025

Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults: A Living Clinical Guideline From the American College of Physicians (Version 1: Update Alert 1: Surveillance Note 1)FREE

Publication: Annals of Internal Medicine
This Surveillance Note 1 alerts readers that a search for new studies was done for the American College of Physicians (ACP) living clinical guideline on “Pharmacologic Treatment of Primary Osteoporosis or Low Bone Mass to Prevent Fractures in Adults” (version 1) (1, 2). The ACP Center for Evidence Reviews at the Portland Veteran Affairs Research Foundation identified no new studies that met inclusion criteria from this surveillance search period between 29 September 2023 (last search date for the Update Alert of version 1 of the living systematic review) to 25 July 2024 (3, 4). The next surveillance is planned for 6 months.
The ACP Clinical Guidelines Committee made a decision that an update of the living systematic review is not warranted at this time because of a lack of any conclusion-changing evidence on benefits or harms from surveillance searches (2). The ACP reaffirms the recommendations in the living clinical guideline on pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults (version 1) (1, 2).

References

1.
Qaseem A, Hicks LA, Etxeandia-Ikobaltzeta I, et al; Clinical Guidelines Committee of the American College of Physicians. Pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults: a living clinical guideline from the American College of Physicians. Ann Intern Med. 2023;176:224-238. [PMID: 36592456] doi: 10.7326/M22-1034
2.
Qaseem A, Hicks LA, Etxeandia-Ikobaltzeta I, et al; Clinical Guidelines Committee of the American College of Physicians. Pharmacologic treatment of primary osteoporosis or low bone mass to prevent fractures in adults: a living clinical guideline from the American College of Physicians (version 1, update alert). Ann Intern Med. 2024;177:eL230113. [PMID: 38710077] doi: 10.7326/L24-0113
3.
Ayers C, Kansagara D, Lazur B, et al. Effectiveness and safety of treatments to prevent fractures in people with low bone mass or primary osteoporosis: a living systematic review and network meta-analysis for the American College of Physicians. Ann Intern Med. 2023;176:182-195. [PMID: 36592455] doi: 10.7326/M22-0684
4.
Ayers C, Ward R, Kansagara D. Update alert: effectiveness and safety of treatments to prevent fractures in people with low bone mass or primary osteoporosis: a living systematic review and network meta-analysis for the American College of Physicians. Ann Intern Med. 2024;177:eL230118. [PMID: 38710084] doi: 10.7326/L24-0118

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Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine

History

Published online: 4 February 2025

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Authors

Affiliations

Amir Qaseem, MD, PhD, MHA https://orcid.org/0000-0001-6866-7985
American College of Physicians, Philadelphia, Pennsylvania
Thomas G. Cooney, MD
Oregon Health & Science University, Portland, Oregon
Tatyana A. Shamliyan, MD, MS
American College of Physicians, Philadelphia, Pennsylvania
Jennifer Yost, PhD, RN
American College of Physicians, Philadelphia, and Villanova University, Villanova, Pennsylvania
Lauri A. Hicks, DO
Centers for Disease Control and Prevention, Atlanta, Georgia
Clinical Guidelines Committee of the American College of Physicians*
Note: Clinical guidelines are meant to guide care based on the best available evidence and may not apply to all patients or individual clinical situations. They should not be used as a replacement for a clinician’s judgment. Any reference to a product or process contained in a guideline is not intended as an endorsement of any specific commercial product. All ACP clinical guidelines are considered automatically withdrawn or invalid 5 years after publication, or once an update has been issued.
Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.
Acknowledgment: Members of the ACP Clinical Guidelines Committee who participated in the development of this project but did not vote or author: Carolyn J. Crandall, MD, MS, Chair. ACP staff who participated in the development of this project but did not vote or author: Kate Carroll, MPH, and Curtis S. Harrod, PhD, MPH.
Financial Support: Financial support for the development of this guideline comes exclusively from the ACP operating budget.
Disclosures: All financial and intellectual disclosures of interest were declared, and potential conflicts were discussed and managed. Dr. Crandall was recused from authorship and voting due to moderate-level conflicts (recently authored relevant publications). A record of disclosures of interest and management of conflicts is kept for each Clinical Guidelines Committee meeting and conference call and can be viewed at www.acponline.org/clinical_information/guidelines/guidelines/conflicts_cgc.htm. Disclosure forms are available with the article online.
Corresponding Author: Amir Qaseem, MD, PhD, MHA, American College of Physicians, 190 N. Independence Mall West, Philadelphia, PA 19106; e-mail, [email protected].
This article was published at Annals.org on 4 February 2025.
*
This article, authored by Amir Qaseem, MD, PhD, MHA; Thomas G. Cooney, MD; Tatyana A. Shamliyan, MD, MS; Jennifer Yost, PhD, RN; and Lauri A. Hicks, DO was developed for the Clinical Guidelines Committee of the American College of Physicians. Members of the Clinical Guidelines Committee who served as authors were Lauri A. Hicks, DO (Vice Chair); Ethan M. Balk, MD, MPH; Thomas G. Cooney, MD; J. Thomas Cross, Jr., MD, MPH; Nick Fitterman, MD; Johanna Lewis, PhD (nonphysician public member); Amy M. Linsky, MD, MSc; Michael Maroto, JD, MBA (nonphysician public member); Matthew C. Miller, MD; Adam J. Obley, MD; Douglas K. Owens, MD, MS; Paul G. Shekelle, MD, PhD, MPH; and Jeffrey A. Tice, MD. Authors from ACP were Itziar Etxeandia-Ikobaltzeta, PharmD, PhD; Amir Qaseem, MD, PhD, MHA; Tatyana A. Shamliyan, MD, MS; and Jennifer Yost, PhD, RN. Approved by the ACP Board of Regents on 18 November 2024.

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