Research and Reporting Methods
2 June 2020

Transparent Reporting of Multivariable Prediction Models in Journal and Conference Abstracts: TRIPOD for Abstracts

Publication: Annals of Internal Medicine
Volume 173, Number 1

Abstract

Clear and informative reporting in titles and abstracts is essential to help readers and reviewers identify potentially relevant studies and decide whether to read the full text. Although the TRIPOD (Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis) statement provides general recommendations for reporting titles and abstracts, more detailed guidance seems to be desirable. The authors present TRIPOD for Abstracts, a checklist and corresponding guidance for reporting prediction model studies in abstracts.
A list of 32 potentially relevant items was the starting point for a modified Delphi procedure involving 110 experts, of whom 71 (65%) participated in the web-based survey. After 2 Delphi rounds, the experts agreed on 21 items as being essential to report in abstracts of prediction model studies. This number was reduced by merging some of the items. In a third round, participants provided feedback on a draft version of TRIPOD for Abstracts.
The final checklist contains 12 items and applies to journal and conference abstracts that describe the development or external validation of a diagnostic or prognostic prediction model, or the added value of predictors to an existing model, regardless of the clinical domain or statistical approach used.

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Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 173Number 17 July 2020
Pages: 42 - 47

History

Published online: 2 June 2020
Published in issue: 7 July 2020

Keywords

Authors

Affiliations

Pauline Heus, MSc
Cochrane Netherlands and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (P.H., J.B.R., J.A.D., R.J.S., K.G.M., L.H.)
Johannes B. Reitsma, MD, PhD
Cochrane Netherlands and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (P.H., J.B.R., J.A.D., R.J.S., K.G.M., L.H.)
Gary S. Collins, PhD
Centre for Statistics in Medicine, Botnar Research Centre, University of Oxford, and National Institute for Health Research Oxford Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom (G.S.C.)
Johanna A.A.G. Damen, PhD
Cochrane Netherlands and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (P.H., J.B.R., J.A.D., R.J.S., K.G.M., L.H.)
Rob J.P.M. Scholten, MD, PhD
Cochrane Netherlands and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (P.H., J.B.R., J.A.D., R.J.S., K.G.M., L.H.)
Douglas G. Altman, DSc†
Centre for Statistics in Medicine, Botnar Research Centre, University of Oxford, Oxford, United Kingdom (D.G.A.)
Karel G.M. Moons, PhD
Cochrane Netherlands and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (P.H., J.B.R., J.A.D., R.J.S., K.G.M., L.H.)
Lotty Hooft, PhD
Cochrane Netherlands and Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands (P.H., J.B.R., J.A.D., R.J.S., K.G.M., L.H.)
Acknowledgment: The authors thank all who contributed to the development of TRIPOD for Abstracts by responding to the Delphi survey. In addition, they thank Romin Pajouheshnia (Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University) for contributing to the assessment of the reporting of prediction model studies in titles and abstracts, and Dr. Jennifer A. de Beyer (Centre for Statistics in Medicine, University of Oxford) for English-language editing.
Grant Support: Dr. Collins was supported by the National Institute for Health Research Biomedical Research Centre, Oxford, United Kingdom, and by programme grant C49297/A27294 from Cancer Research UK. Dr. Moons received grants from the Netherlands Organization for Scientific Research (ZONMW 918.10.615 and 91208004).
Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M20-0193.
Corresponding Author: Pauline Heus, MSc, Cochrane Netherlands, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Str. 6.131, PO Box 85500, 3508 GA Utrecht, the Netherlands; e-mail, [email protected].
Current Author Addresses: Ms. Heus and Drs. Reitsma, Damen, Scholten, Moons, and Hooft: Cochrane Netherlands, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Str. 6.131, PO Box 85500, 3508 GA Utrecht, the Netherlands.
Dr. Collins: Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford OX3 7LD, United Kingdom.
Author Contributions: Conception and design: P. Heus, J.B. Reitsma, G.S. Collins, J.A.A.G. Damen, D.G. Altman, K.G.M. Moons, L. Hooft.
Analysis and interpretation of the data: P. Heus, J.B. Reitsma, G.S. Collins, J.A.A.G. Damen, R.J.P.M. Scholten, D.G. Altman, K.G.M. Moons, L. Hooft.
Drafting of the article: P. Heus, J.B. Reitsma, K.G.M. Moons.
Critical revision of the article for important intellectual content: P. Heus, J.B. Reitsma, G.S. Collins, J.A.A.G. Damen, R.J.P.M. Scholten, D.G. Altman, K.G.M. Moons, L. Hooft.
Final approval of the article: P. Heus, J.B. Reitsma, G.S. Collins, J.A.A.G. Damen, R.J.P.M. Scholten, K.G.M. Moons, L. Hooft.
Provision of study materials or patients: K.G.M. Moons.
Statistical expertise: G.S. Collins, D.G. Altman, K.G.M. Moons.
Obtaining of funding: G.S. Collins, K.G.M. Moons.
Administrative, technical, or logistic support: P. Heus, G.S. Collins, K.G.M. Moons.
Collection and assembly of data: P. Heus, G.S. Collins, J.A.A.G. Damen, R.J.P.M. Scholten, K.G.M. Moons, L. Hooft.
This article was published at Annals.org on 2 June 2020.
† Deceased.

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Pauline Heus, Johannes B. Reitsma, Gary S. Collins, et al. Transparent Reporting of Multivariable Prediction Models in Journal and Conference Abstracts: TRIPOD for Abstracts. Ann Intern Med.2020;173:42-47. [Epub 2 June 2020]. doi:10.7326/M20-0193

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