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19 May 2015

Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD)

Author: Harry B. Burke, MD, PhDAuthor, Article, & Disclosure Information
Publication: Annals of Internal Medicine
Volume 162, Number 10
https://doi.org/10.7326/L15-5093
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TO THE EDITOR:
Collins and colleagues' article (1) is important because prediction is becoming an integral part of clinical medicine. I was gratified to note their statement that all predictions must be time-denominated (2). The authors suggest that there are only 2 types of predictions, diagnostic and prognostic, and subsume risk predictions within diagnostic predictions. I have suggested that risk is a third type of prediction (3).
Risk and diagnostic predictions differ in their targets, degrees of predictive accuracy, and time intervals. In diagnostic predictions, we wish to predict whether a person has detectable disease, the disease's …

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References

1.
Collins GS, Reitsma JB, Altman DG, Moons KG. Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis (TRIPOD): the TRIPOD statement. Ann Intern Med. 2015;162:55-63. [PMID: 25560714]  doi: 10.7326/M14-0697
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2.
Burke HB. The power of prediction [Editorial]. Cancer. 2008;113:890-2. [PMID: 18615664]  doi: 10.1002/cncr.23675
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3.
Burke HB. Increasing the power of surrogate endpoint biomarkers: the aggregation of predictive factors. J Cell Biochem Suppl. 1994;19:278-82. [PMID: 7823601]
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4.
Burke HB, Grizzle WE. Clinical validation of molecular biomarkers in translational medicine. In: Srivastava S, eds. Biomarkers in Cancer Screening and Early Detection. Oxford, United Kingdom: Wiley; 2015 [Forthcoming].
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Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 162 • Number 10 • 19 May 2015
Pages: 735

History

Published online: 19 May 2015
Published in issue: 19 May 2015

Keywords

  1. Conflicts of interest
  2. Disclosure

Copyright

© 2015 American College of Physicians.

Authors

Affiliations

Harry B. Burke, MD, PhD
From Uniformed Services University of the Health Sciences, Bethesda, Maryland.
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Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterest Forms.do?msNum=L15-0100.

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Harry B. Burke. Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD). Ann Intern Med.2015;162:735. [Epub 19 May 2015]. doi:10.7326/L15-5093

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