Systemic Lupus Erythematosus and Latent Renal Tubular Dysfunction
Publication: Annals of Internal Medicine
Volume 67, Number 1
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Renal tubular acidosis (1), an impairment of renal acid excretion out of proportion to reduction of glomerular filtration rate, has been described in a variety of clinical settings. Its characteristic clinical manifestations are hyperchloremic acidosis, an inability to excrete a highly acid urine, and impaired renal concentrating ability. It may be associated, in the primary form, with renal calculi, nephrocalcinosis, osteomalacia, and potassium depletion (2). Subclinical cases—either asymptomatic or lacking the laboratory findings of the overt cases of renal tubular acidosis—have been uncovered by an acid-loading test designed to detect acid excretion inappropriate to the induced metabolic acidosis (3, 4)....
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SHEARN MA and TU WH: Latent renal tubular acidosis in Sjögren's syndrome. In preparation.
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Published In
Annals of Internal Medicine
Volume 67 • Number 1 • 1 July 1967
Pages: 100 - 109
History
Published in issue: 1 July 1967
Published online: 1 December 2008
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Systemic Lupus Erythematosus and Latent Renal Tubular Dysfunction. Ann Intern Med.1967;67:100-109. doi:10.7326/0003-4819-67-1-100
Systemic Lupus Erythematosus and Latent Renal Tubular Dysfunction. Ann Intern Med.1967;67:100-109. doi:10.7326/0003-4819-67-1-100
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