Abstract
This National Institutes of Health (NIH) Pathways to Prevention Workshop was cosponsored by the NIH Office of Disease Prevention (ODP), the NIH Pain Consortium, the National Institute on Drug Abuse, and the National Institute of Neurological Disorders and Stroke. A multidisciplinary working group developed the workshop agenda, and an evidence-based practice center prepared an evidence report through a contract with the Agency for Healthcare Research and Quality to facilitate the workshop discussion. During the 1.5-day workshop, invited experts discussed the body of evidence, and attendees had opportunities to provide comments during open discussion periods. After weighing evidence from the evidence report, expert presentations, and public comments, an unbiased, independent panel prepared a draft report that identified research gaps and future research priorities. The report was posted on the ODP Web site for 2 weeks for public comment. This article is an abridged version of the panel's full report, which is available at https://prevention.nih.gov/programs-events/pathways-to-prevention/workshops/opioids-chronic-pain/workshop-resources#final report.
References
- 1.
Chou R ,Turner JA ,Devine EB ,Hansen RN ,Sullivan SD ,Blazina I ,et al . The effectiveness and risks of long-term opioid therapy for chronic pain: a systematic review for a National Institutes of Health Pathways to Prevention workshop. Ann Intern Med. 2015;162:276-86. doi:10.7326/M14-2559 LinkGoogle Scholar - 2.
Substance Abuse and Mental Health Services Administration . Results from the 2013 National Survey on Drug Use and Health: Summary of National Findings. NSDUH series H-48. HHS publication no. (SMA) 14-4863. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2014. Google Scholar - 3. Warner M, Hedegaard H, Chen LH. NCHS Health E-Stat: Trends in Drug-poisoning Deaths Involving Opioid Analgesics and Heroin: United States, 1999–2012. Atlanta, GA: Centers for Disease Control and Prevention; 2014. Accessed at www.cdc.gov/nchs/data/hestat/drug_poisoning/drug_poisoning.htm on 22 December 2014. Google Scholar
- 4.
Gomes T ,Mamdani MM ,Dhalla IA ,Cornish S ,Paterson JM ,Juurlink DN . The burden of premature opioid-related mortality. Addiction. 2014;109:1482-8. [PMID: 25041316] doi:10.1111/add.12598 CrossrefMedlineGoogle Scholar
Author, Article, and Disclosure Information
David B. Reuben,
From David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California; Johns Hopkins University, Baltimore, Maryland; University of Vermont, Burlington, Vermont; Michigan State University, East Lansing, Michigan; Indiana University Center for Aging Research and Regenstrief Institute, Indianapolis, Indiana; and University of Connecticut Health Center, Farmington, Connecticut.
Note: A list of the workshop panelists, speakers, working group members, and sponsors is provided in the Appendix.
Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M14-2775.
Corresponding Author: David B. Reuben, MD, Division of Geriatrics, David Geffen School of Medicine at the University of California, Los Angeles, 10945 Le Conte Avenue, Los Angeles, CA 90095.
Current Author Addresses: Dr. Reuben: Division of Geriatrics, David Geffen School of Medicine at the University of California, Los Angeles, 10945 Le Conte Avenue, Los Angeles, CA 90095.
Dr. Alvanzo: Johns Hopkins University School of Medicine, 1830 East Monument Street, Room 8069, Baltimore, MD 21287.
Dr. Ashikaga: University of Vermont, 105 Carrigan Drive, Medical Biostatistics, 27 Hills Building, Burlington, VT 05405.
Dr. Bogat: Department of Psychology, Michigan State University, 107E Psychology Building, East Lansing, MI 48824-1116.
Dr. Callahan: Indiana University Center for Aging Research, Regenstrief Institute, 410 West 10th Street, Building HS2000, Indianapolis, IN 46202.
Ms. Ruffing: Johns Hopkins University, 5501 Hopkins Bayview Circle, JHAAC 1B1, Baltimore, MD 21224.
Dr. Steffens: University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-1410.
Author Contributions: Conception and design: D.B. Reuben, G.A. Bogat, C.M. Callahan, D.C. Steffens.
Analysis and interpretation of the data: D.B. Reuben, T. Ashikaga, G.A. Bogat.
Drafting of the article: D.B. Reuben, A.A.H. Alvanzo, T. Ashikaga, G.A. Bogat, C.M. Callahan, V. Ruffing, D.C. Steffens.
Critical revision of the article for important intellectual content: D.B. Reuben, T. Ashikaga, G.A. Bogat, C.M. Callahan, D.C. Steffens.
Final approval of the article: D.B. Reuben, A.A.H. Alvanzo, T. Ashikaga, G.A. Bogat, C.M. Callahan, V. Ruffing, D.C. Steffens.
Statistical expertise: T. Ashikaga, G.A. Bogat.
This article was published online first at www.annals.org on 13 January 2015.
Submit a Comment
Contributors must reveal any conflict of interest. Comments are moderated. Please see our information for authorsregarding comments on an Annals publication.
*All comments submitted after October 1, 2021 and selected for publication will be published online only.