Until recently, the silent epidemic of viral hepatitis has eluded a unified national public health strategy for controlling morbidity and mortality. Consequently, untreated chronic viral hepatitis affects between 3.5 and 5.3 million Americans and continues to fuel rising rates of progressive liver disease, liver failure, and liver cancer (1). Chronic hepatitis C virus (HCV) infection affects some 2.7 million noninstitutionalized Americans (2), represents the leading indication for liver transplantation in the United States (3), and has caused more deaths annually than HIV since 2007 (4). Although effective vaccination strategies have contributed to a decline in new cases of acute hepatitis ...

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