Original Research
7 October 2014

Support From Hospital to Home for Elders: A Randomized Trial

Publication: Annals of Internal Medicine
Volume 161, Number 7

Abstract

Background:

Hospitals are implementing discharge support programs to reduce readmissions, and these programs have had mixed success.

Objective:

To examine whether a peridischarge, nurse-led intervention decreased emergency department (ED) visits or readmissions among ethnically and linguistically diverse older patients admitted to a safety-net hospital.

Design:

Randomized, controlled trial using computer-generated randomization with 1:1 allocation, stratified by language. (Clinical Trials.gov: NCT01221532)

Setting:

Publicly funded urban hospital in Northern California.

Patients:

Hospitalized adults aged 55 years or older with anticipated discharge to the community who spoke English, Spanish, or Chinese (Mandarin or Cantonese).

Intervention:

Usual care versus in-hospital, one-on-one, self-management education given by a dedicated language-concordant registered nurse combined with a telephone follow-up after discharge from a nurse practitioner.

Measurements:

Staff blinded to the study groups determined ED visits or readmissions to any facility at 30, 90, and 180 days after initial hospital discharge using administrative data from several hospitals.

Results:

There were 700 low-income, ethnically and linguistically diverse patients with a mean age of 66.2 years (SD, 9.0). The primary outcome of ED visits or readmissions did not differ between the intervention and usual care groups (hazard ratio, 1.26 [95% CI, 0.89 to 1.78] at 30 days, 1.21 [CI, 0.91 to 1.62] at 90 days, and 1.11 [CI, 0.86 to 1.43] at 180 days).

Limitations:

This study was done at a single acute-care hospital. There were fewer outcomes than expected, which may have caused the study to be underpowered.

Conclusion:

A nurse-led, in-hospital discharge support intervention did not show a reduction in readmissions or ED visits among diverse, low-income older adults at a safety-net hospital. Although wide CIs preclude firm conclusions, the intervention may have increased ED visits. Alternative readmission prevention strategies should be tested in this population.

Primary Funding Source:

Gordon and Betty Moore Foundation.

Get full access to this article

View all available purchase options and get full access to this article.

Supplemental Material

Supplement 1. Methods for RN Training, Ascertainment of Outcomes, and Sensitivity Analyses

Supplement 2. Results of Sensitivity Analyses

References

1.
Forster AJMurff HJPeterson JFGandhi TKBates DW. The incidence and severity of adverse events affecting patients after discharge from the hospital. Ann Intern Med. 2003;138:161-7. [PMID: 12558354]
2.
Oddone EZWeinberger MHorner MMengel CGoldstein FGinier Pet al. Classifying general medicine readmissions. Are they preventable? Veterans Affairs Cooperative Studies in Health Services Group on Primary Care and Hospital Readmissions. J Gen Intern Med. 1996;11:597-607. [PMID: 8945691]
3.
Centers for Medicare & Medicaid Services. Accountable Care Organizations (ACO). Accessed at www.cms.gov/Medicare/Medicare-Fee-for-Service-Payment/ACO/index.html?redirect=/aco on 8 August 2013.
4.
U.S. Department of Health and Human Services. Understanding the Affordable Care Act: About the Law. Accessed at www.hhs.gov/healthcare/rights/index.html on 4 August 2014.
5.
Balaban RBWeissman JSSamuel PAWoolhandler S. Redefining and redesigning hospital discharge to enhance patient care: a randomized controlled study. J Gen Intern Med. 2008;23:1228-33. [PMID: 18452048]  doi: 10.1007/s11606-008-0618-9
6.
Brown-Williams H, Neuhauser L, Ivey S, Graham C, Poor S, Tseng W, et al. From Hospital to Home: Improving Transitional Care for Older Adults. Berkeley, CA: University of California, Berkeley; 2006. Accessed at www.healthresearchforaction.org/sites/default/files/REPORT_PUBS_H2H%20FNL.pdf on 4 August 2014.
7.
Dudas VBookwalter TKerr KMPantilat SZ. The impact of follow-up telephone calls to patients after hospitalization. Dis Mon. 2002;48:239-48. [PMID: 12021756]
8.
Jack BWChetty VKAnthony DGreenwald JLSanchez GMJohnson AEet al. A reengineered hospital discharge program to decrease rehospitalization: a randomized trial. Ann Intern Med. 2009;150:178-87. [PMID: 19189907]
9.
Naylor MD. Transitional care of older adults. Annu Rev Nurs Res. 2002;20:127-47. [PMID: 12092508]
10.
Naylor MDBrooten DACampbell RLMaislin GMcCauley KMSchwartz JS. Transitional care of older adults hospitalized with heart failure: a randomized, controlled trial. J Am Geriatr Soc. 2004;52:675-84. [PMID: 15086645]
11.
Coleman EAParry CChalmers SMin SJ. The care transitions intervention: results of a randomized controlled trial. Arch Intern Med. 2006;166:1822-8. [PMID: 17000937]
12.
Naylor MD. Transitional care for older adults: a cost-effective model. LDI Issue Brief. 2004;9:1-4. [PMID: 15181894]
14.
Hansen LOGreenwald JLBudnitz THowell EHalasyamani LMaynard Get al. Project BOOST: effectiveness of a multihospital effort to reduce rehospitalization. J Hosp Med. 2013;8:421-7. [PMID: 23873709]  doi: 10.1002/jhm.2054
15.
Shin H, Bruno R. Language Use and English-Speaking Ability: 2000. Census 2000 Brief. Washington, DC: U.S. Census Bureau; 2003. Accessed at www.census.gov/prod/2003pubs/c2kbr-29.pdf on 28 July 2014.
16.
Marengoni AWinblad BKarp AFratiglioni L. Prevalence of chronic diseases and multimorbidity among the elderly population in Sweden. Am J Public Health. 2008;98:1198-200. [PMID: 18511722]  doi: 10.2105/AJPH.2007.121137
17.
Society of Hospital Medicine. How to Use Project BOOST Implementation Toolkit. Accessed at https://store.hospitalmedicine.org/Web/Quality___Innovation/Implementation_Toolkit/Boost/Home/How_To_Use.aspxon 6 August 2014.
18.
Joint Commission Resources. Project RED. Accessed at www.jcrinc.com/about-jcr/project-red on 21 April 2014.
19.
Lewin MEAltman Seds. America's Health Care Safety Net: Intact but Endangered. Washington, DC: National Academies Pr; 2000.
20.
Campbell SESeymour DGPrimrose WRACMEPLUS Project. A systematic literature review of factors affecting outcome in older medical patients admitted to hospital. Age Ageing. 2004;33:110-5. [PMID: 14960424]
21.
Volz ASchmid JPZwahlen MKohls SSaner HBarth J. Predictors of readmission and health related quality of life in patients with chronic heart failure: a comparison of different psychosocial aspects. J Behav Med. 2011;34:13-22. [PMID: 20658185]  doi: 10.1007/s10865-010-9282-8
22.
Cawthon PMFox KMGandra SRDelmonico MJChiou CFAnthony MSet alHealth, Aging and Body Composition Study. Do muscle mass, muscle density, strength, and physical function similarly influence risk of hospitalization in older adults? J Am Geriatr Soc. 2009;57:1411-9. [PMID: 19682143]  doi: 10.1111/j.1532-5415.2009.02366.x
23.
Williams MVDavis TParker RMWeiss BD. The role of health literacy in patient-physician communication. Fam Med. 2002;34:383-9. [PMID: 12038721]
24.
Cunningham PJBazzoli GJKatz A. Caught in the competitive crossfire: safety-net providers balance margin and mission in a profit-driven health care market. Health Aff (Millwood). 2008;27:w374-82. [PMID: 18697764]  doi: 10.1377/hlthaff.27.5.w374
25.
Joynt KEJha AK. A path forward on Medicare readmissions. N Engl J Med. 2013;368:1175-7. [PMID: 23465069]  doi: 10.1056/NEJMp1300122
26.
Jha AK. BOOST and readmissions: thinking beyond the walls of the hospital [Editorial]. J Hosp Med. 2013;8:470-1. [PMID: 23873761]  doi: 10.1002/jhm.2069
27.
Ness D, Kramer W. Reducing Hospital Readmissions: It's About Improving Patient Care. 16 August 2013. Accessed at http://healthaffairs.org/blog/2013/08/16/reducing-hospital-readmissions-its-about-improving-patient-care on 22 April 2014.
28.
Sudore RLLandefeld CSWilliams BABarnes DELindquist KSchillinger D. Use of a modified informed consent process among vulnerable patients: a descriptive study. J Gen Intern Med. 2006;21:867-73. [PMID: 16881949]
29.
Searight HR. Efficient counseling techniques for the primary care physician. Prim Care. 2007;34:551-70, vi-vii. [PMID: 17868759]
30.
Huang L. Krames On-Demand (KOD). J Med Libr Assoc. 2006;94:234-5.
31.
Schillinger DPiette JGrumbach KWang FWilson CDaher Cet al. Closing the loop: physician communication with diabetic patients who have low health literacy. Arch Intern Med. 2003;163:83-90. [PMID: 12523921]
32.
Schillinger DHandley MWang FHammer H. Effects of self-management support on structure, process, and outcomes among vulnerable patients with diabetes: a three-arm practical clinical trial. Diabetes Care. 2009;32:559-66. [PMID: 19131469]  doi: 10.2337/dc08-0787
33.
Operario DAdler NEWilliams DR. Subjective social status: reliability and predictive utility for global health. Psychol Health. 2004;19:237-46.
34.
Ware J JrKosinski MKeller SD. A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996;34:220-33. [PMID: 8628042]
35.
Katz SFord ABMoskowitz RWJackson BAJaffe MW. Studies of illness in the aged. The index of ADL: a standardized measure of biological and psychosocial function. JAMA. 1963;185:914-9. [PMID: 14044222]
36.
Lawton MPBrody EM. Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist. 1969;9:179-86. [PMID: 5349366]
37.
de Jager CABudge MMClarke R. Utility of TICS-M for the assessment of cognitive function in older adults. Int J Geriatr Psychiatry. 2003;18:318-24. [PMID: 12673608]
38.
Debling DAmelang MHasselbach PStürmer T. Assessment of cognitive status in the elderly using telephone interviews. Z Gerontol Geriatr. 2005;38:360-7. [PMID: 16244822]
39.
Centers for Disease Control and Prevention. 2008 National Health Interview Survey (NHIS): Public Use Data Release. 2009. Accessed at http://ftp.cdc.gov/pub/Health_Statistics/NCHS/Dataset_Documentation/NHIS/2008/srvydesc.pdf on 6 August 2014.
40.
WHO ASSIST Working Group. The Alcohol, Smoking and Substance Involvement Screening Test (ASSIST): development, reliability and feasibility. Addiction. 2002;97:1183-94. [PMID: 12199834]
41.
Spitzer RLKroenke KWilliams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. JAMA. 1999;282:1737-44. [PMID: 10568646]
42.
Reuland DSCherrington AWatkins GSBradford DWBlanco RAGaynes BN. Diagnostic accuracy of Spanish language depression-screening instruments. Ann Fam Med. 2009;7:455-62. [PMID: 19752474]  doi: 10.1370/afm.981
43.
Chew LDBradley KABoyko EJ. Brief questions to identify patients with inadequate health literacy. Fam Med. 2004;36:588-94. [PMID: 15343421]
44.
Sarkar USchillinger DLópez ASudore R. Validation of self-reported health literacy questions among diverse English and Spanish-speaking populations. J Gen Intern Med. 2011;26:265-71. [PMID: 21057882]  doi: 10.1007/s11606-010-1552-1
45.
Charlson MEPompei PAles KLMacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373-83. [PMID: 3558716]
46.
Kleinbaum DGKlein M. Survival Analysis: A Self-Learning Text. 3rd ed. New York: Springer; 2012.
47.
Schafer JLGraham JW. Missing data: our view of the state of the art. Psychol Methods. 2002;7:147-77. [PMID: 12090408]
48.
Hernán MAHernández-Díaz SRobins JM. Randomized trials analyzed as observational studies. Ann Intern Med. 2013;159:560-2. [PMID: 24018844]
49.
Shepperd SMcClaran JPhillips COLannin NAClemson LMMcCluskey Aet al. Discharge planning from hospital to home. Cochrane Database Syst Rev. 2010:CD000313. [PMID: 20091507]  doi: 10.1002/14651858.CD000313.pub3
50.
Hesselink GSchoonhoven LBarach PSpijker AGademan PKalkman Cet al. Improving patient handovers from hospital to primary care: a systematic review. Ann Intern Med. 2012;157:417-28. [PMID: 22986379]  doi: 10.7326/0003-4819-157-6-201209180-00006
51.
Hansen LOYoung RSHinami KLeung AWilliams MV. Interventions to reduce 30-day rehospitalization: a systematic review. Ann Intern Med. 2011;155:520-8. [PMID: 22007045]  doi: 10.7326/0003-4819-155-8-201110180-00008
52.
McCarthy DJohnson MBAudet AM. Recasting readmissions by placing the hospital role in community context. JAMA. 2013;309:351-2. [PMID: 23340635]  doi: 10.1001/jama.2013.1
53.
Naylor MDBrooten DCampbell RJacobsen BSMezey MDPauly MVet al. Comprehensive discharge planning and home follow-up of hospitalized elders: a randomized clinical trial. JAMA. 1999;281:613-20. [PMID: 10029122]
54.
Gerhardt G, Yemane A, Hickman P, Oelschlaeger A, Rollins E, Brennan N. Data Shows Reduction in Medicare Hospital Readmission Rates During 2012. Medicare & Medicaid Research Review. 2013;3. Accessed at www.cms.gov/mmrr/Downloads/MMRR2013_003_02_b01.pdf on 4 August 2014.
55.
Fan VSGaziano JMLew RBourbeau JAdams SGLeatherman Set al. A comprehensive care management program to prevent chronic obstructive pulmonary disease hospitalizations: a randomized, controlled trial. Ann Intern Med. 2012;156:673-83. [PMID: 22586006]  doi: 10.7326/0003-4819-156-10-201205150-00003
56.
Urbach DRGovindarajan ASaskin RWilton ASBaxter NN. Introduction of surgical safety checklists in Ontario, Canada. N Engl J Med. 2014;370:1029-38. [PMID: 24620866]  doi: 10.1056/NEJMsa1308261

Comments

0 Comments
Sign In to Submit A Comment

Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 161Number 77 October 2014
Pages: 472 - 481

History

Published online: 7 October 2014
Published in issue: 7 October 2014

Keywords

Authors

Affiliations

L. Elizabeth Goldman, MD, MCR
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Urmimala Sarkar, MD, MPH
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Eric Kessell, PhD
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
David Guzman, MS
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Michelle Schneidermann, MD
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Edgar Pierluissi, MD
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Barbara Walter, RN, MSN
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Eric Vittinghoff, PhD, MPH
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Jeff Critchfield, MD
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Margot Kushel, MD
From San Francisco General Hospital, University of California, San Francisco, San Francisco, California.
Acknowledgment: The authors thank Sue Currin, MS, RN, Chief Executive Officer of San Francisco General Hospital Medical Center, for helping to secure funding for this study; San Francisco General Hospital for providing in-kind support; Michael Paasche-Orlow, MD, for his collaboration; and Jenna Kruger, MS, for helping to prepare and submit the manuscript. They thank Richard Santana, RN; Catheryn Williams, RN; Tip Tam, RN, for implementing the intervention. The authors also thank the study nurse practitioners and research assistants for their invaluable contribution to this study.
Grant Support: The Gordon and Betty Moore Foundation (grant 1836), the Agency for Healthcare Research and Quality (grant K08 HS018090-01), and the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, through the University of California, San Francisco Clinical and Translational Science Institute (grant KL2 RR024130).
Reproducible Research Statement: Study protocol: Available from Dr. Goldman (email, [email protected]). Statistical code and data set: Not available.
Corresponding Author: L. Elizabeth Goldman, MD, MCR, Department of Internal Medicine, Division of General Medicine, San Francisco General Hospital, University of California, San Francisco, 1001 Potrero Avenue, Box 1364, San Francisco, CA, 94110; e-mail, [email protected].
Current Author Addresses: Drs. Goldman, Sarkar, and Kushel and Mr. Guzman: Department of Internal Medicine, Division of General Medicine, San Francisco General Hospital, University of California, San Francisco, 1001 Potrero Avenue, Box 1364, San Francisco, CA, 94110.
Drs. Kessell, Schneidermann, Pierlussi, and Critchfield: Department of Medicine, Division of General Medicine, San Francisco General Hospital, University of California, San Francisco, 1001 Potrero Avenue, Room 5H17, San Francisco, CA 94110.
Ms. Walter: HealthWorks4U, RN Healthcare Consultants, 115 Third Street, Suite 2, San Rafael, CA 94904.
Dr. Vittinghoff: Division of Biostatistics, Department of Epidemiology and Biostatistics, University of California, San Francisco, 185 Berry Street, Lobby 5, Suite 5700, San Francisco, CA 94107.
Author Contributions: Conception and design: L.E. Goldman, U. Sarkar, E. Kessell, M. Schneidermann, E. Pierluissi, B. Walter, J. Critchfield, M. Kushel.
Analysis and interpretation of the data: L.E. Goldman, U. Sarkar, E. Kessell, D. Guzman, E. Pierluissi, E. Vittinghoff, J. Critchfield, M. Kushel.
Drafting of the article: L.E. Goldman, U. Sarkar, E. Kessell, D. Guzman, M. Schneidermann, J. Critchfield, M. Kushel.
Critical revision of the article for important intellectual content: L.E. Goldman, E. Kessell, D. Guzman, M. Schneidermann, E. Pierluissi, E. Vittinghoff, J. Critchfield, M. Kushel.
Final approval of the article: L.E. Goldman, U. Sarkar, J. Critchfield, M. Kushel.
Provision of study materials or patients: M. Schneidermann, B. Walter, J. Critchfield.
Statistical expertise: D. Guzman, E. Vittinghoff.
Obtaining of funding: J. Critchfield.
Administrative, technical, or logistic support: E. Kessell, M. Schneidermann, B. Walter, J. Critchfield.
Collection and assembly of data: L.E. Goldman, U. Sarkar, E. Kessell, D. Guzman, M. Schneidermann, B. Walter, J. Critchfield, M. Kushel.
* Drs. Goldman and Sarkar contributed equally to this work.

Metrics & Citations

Metrics

Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. For an editable text file, please select Medlars format which will download as a .txt file. Simply select your manager software from the list below and click Download.

For more information or tips please see 'Downloading to a citation manager' in the Help menu.

Format





Download article citation data for:
L. Elizabeth Goldman, Urmimala Sarkar, Eric Kessell, et al. Support From Hospital to Home for Elders: A Randomized Trial. Ann Intern Med.2014;161:472-481. [Epub 7 October 2014]. doi:10.7326/M14-0094

View More

Login Options:
Purchase

You will be redirected to acponline.org to sign-in to Annals to complete your purchase.

Access to EPUBs and PDFs for FREE Annals content requires users to be registered and logged in. A subscription is not required. You can create a free account below or from the following link. You will be redirected to acponline.org to create an account that will provide access to Annals. If you are accessing the Free Annals content via your institution's access, registration is not required.

Create your Free Account

You will be redirected to acponline.org to create an account that will provide access to Annals.

View options

PDF/EPUB

View PDF/EPUB

Related in ACP Journals

Full Text

View Full Text

Figures

Tables

Media

Share

Share

Copy the content Link

Share on social media