Background: Celiac disease is an autoimmune and gluten-induced enteropathy with a worldwide prevalence of around 1%. The only proven treatment is strict and lifelong adherence to a gluten-free diet (1). Although dietary adherence is crucial for mucosal healing and prevention of long-term complications, complete avoidance of gluten is difficult for even the most committed patients. Nondietary treatments for celiac disease have no established efficacy.
Objective: To report what we believe to be the first case of serologic and histologic remission of adult celiac disease with tofacitinib despite a gluten-containing diet.
Case Report: A male patient with a histologically and serologically ...
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Author, Article and Disclosure Information
University Hospitals Leuven, Leuven, Belgium (L.W., T.V., M.H.)
Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L20-0497.
Corresponding Author: Lucas Wauters, MD, Department of Gastroenterology and Hepatology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium; e-mail, lucas.
This article was published at Annals.org on 28 July 2020.
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