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7 January 2020

Effects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes

Author: Martin Mayer, DMSc, MS, PA-CAuthor, Article, & Disclosure Information
Publication: Annals of Internal Medicine
Volume 172, Number 1
https://doi.org/10.7326/L19-0715
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TO THE EDITOR:
I applaud Khan and colleagues (1) for taking on the substantial task of performing an umbrella review on nutritional supplements and dietary interventions on cardiovascular outcomes. However, their results for salt reduction for the outcome of all-cause mortality in patients without hypertension deserve additional scrutiny. They cite a Cochrane review (2) as the sole source for this outcome, and the number of events and participants are consistent with that review's analysis for all-cause mortality at longest follow-up.
The RR point estimates in both the Cochrane review and Khan and colleagues' review are 0.90, but the …

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References

1.
Khan SU, Khan MU, Riaz H, et al. Effects of nutritional supplements and dietary interventions on cardiovascular outcomes: an umbrella review and evidence map. Ann Intern Med. 2019;171:190-8. [PMID: 31284304].  doi: 10.7326/M19-0341
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Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 172 • Number 1 • 7 January 2020
Pages: 74

History

Published online: 7 January 2020
Published in issue: 7 January 2020

Keywords

  1. Conflicts of interest
  2. Disclosure
  3. Hypertension
  4. Mortality
  5. Nutrition
  6. Salts
  7. Statistical data

Copyright

© 2020 American College of Physicians.

Authors

Affiliations

Martin Mayer, DMSc, MS, PA-C
EBSCO Health and Triad Hospitalist Group, Cone Health, Greensboro, North Carolina (M.M.)
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Disclosures: The author has disclosed no conflicts of interest. The form can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L19-0715.

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Martin Mayer. Effects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes. Ann Intern Med.2020;172:74. [Epub 7 January 2020]. doi:10.7326/L19-0715

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