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ACP Journal Club
2 January 2024

In ICU patients not receiving early PN, tight and liberal glucose control did not differ for length of ICU stay or death

Authors: Kimia Honarmand, MD, and Simon Oczkowski, MDAuthor, Article, & Disclosure Information
Publication: Annals of Internal Medicine
Volume 177, Number 1
https://doi.org/10.7326/J23-0109
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Abstract

Source Citation

Gunst J, Debaveye Y, Güiza F, et al; TGC-Fast Collaborators. Tight blood-glucose control without early parenteral nutrition in the ICU. N Engl J Med. 2023;389:1180-1190. https://pubmed.ncbi.nlm.nih.gov/37754283/

Abstract

Clinical Impact Ratings

GIM/FP/GP: 5 out of 7
Endocrinology: 5 out of 7
Critical Care: 5 out of 7

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References

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van den Berghe G, Wouters P, Weekers F, et al. Intensive insulin therapy in critically ill patients. N Engl J Med. 2001;345:1359-1367. [PMID: 11794168]
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NICE-SUGAR Study Investigators; Finfer S, Chittock DR, Su SY, et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009;360:1283-1297. [PMID: 19318384]
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NICE-SUGAR Study Investigators; Finfer S, Liu B, Chittock DR, et al. Hypoglycemia and risk of death in critically ill patients. N Engl J Med. 2012;367:1108-1118. [PMID: 22992074]
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Casaer MP, Mesotten D, Hermans G, et al. Early versus late parenteral nutrition in critically ill adults. N Engl J Med. 2011;365:506-517. [PMID: 21714640]
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Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 177 • Number 1 • January 2024
Pages: JC8

History

Published online: 2 January 2024
Published in issue: January 2024

Keywords

  1. Algorithms
  2. Blood
  3. Computers
  4. Glucose
  5. Hypoglycemia
  6. Insulin
  7. Intensive care units
  8. Mortality
  9. Nutrition
  10. Randomized trials

Copyright

© 2024 American College of Physicians.

Authors

Affiliations

Kimia Honarmand, MD
Mackenzie Health, Vaughn, Ontario, Canada (K.H.)
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Simon Oczkowski, MD
McMaster University, Hamilton, Ontario, Canada (S.O.)
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This article was published at Annals.org on 2 January 2024.
ACP Journal Club is editorially independent from Annals of Internal Medicine.

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Kimia Honarmand, Simon Oczkowski. In ICU patients not receiving early PN, tight and liberal glucose control did not differ for length of ICU stay or death. Ann Intern Med.2024;177:JC8. [Epub 2 January 2024]. doi:10.7326/J23-0109

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