ACP Journal Club
3 September 2024

In T2DM with CKD, semaglutide reduced major kidney disease events at 3 y

Publication: Annals of Internal Medicine
Volume 177, Number 9

Abstract

Source Citation

Perkovic V, Tuttle KR, Rossing P, et al; FLOW Trial Committees and Investigators. Effects of semaglutide on chronic kidney disease in patients with type 2 diabetes. N Engl J Med. 2024;391:109-121. https://pubmed.ncbi.nlm.nih.gov/38785209/

Abstract

Clinical Impact Ratings

GIM/FP/GP: 6 out of 7
Endocrinology: 6 out of 7
Nephrology: 6 out of 7

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References

1.
Guyatt GH, Briel M, Glasziou P, et al. Problems of stopping trials early. BMJ. 2012;344:e3863. [PMID: 22705814]
2.
Apperloo EM, Neuen BL, Fletcher RA, et al. Efficacy and safety of SGLT2 inhibitors with and without glucagon-like peptide 1 receptor agonists: a SMART-C Collaborative meta-analysis of randomised controlled trials. Lancet Diabetes Endocrinol. 2024;12:545-557. [PMID: 38991584]

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Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 177Number 9September 2024
Pages: JC98

History

Published online: 3 September 2024
Published in issue: September 2024

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Authors

Affiliations

David Collister, MD, PhD https://orcid.org/0000-0002-2323-6521
University of Alberta and Hamilton Health Sciences, Edmonton, Alberta, and Hamilton, Ontario, Canada (D.C.)
Neesh Pannu, MD, SM
University of Alberta, Edmonton, Alberta, Canada (N.P.)
Disclosures: Disclosure forms are available with the article online.
This article was published at Annals.org on 3 September 2024.
ACP Journal Club is editorially independent from Annals of Internal Medicine.

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David Collister, Neesh Pannu. In T2DM with CKD, semaglutide reduced major kidney disease events at 3 y. Ann Intern Med.2024;177:JC98. [Epub 3 September 2024]. doi:10.7326/ANNALS-24-01579-JC

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