Editorial
January 1, 2006

An emerging consensus on grading recommendations?

Publication: ACP Journal Club
Volume 144, Number 1
Clinical practice guidelines have improved in quality over the past 10 years by adhering to a few basic principles, such as conducting thorough systematic reviews of relevant evidence and grading the recommendations and the quality of the underlying evidence. The large number of systems of measuring the quality of evidence and recommendations that have emerged are, however, confusing (1).
The mission of the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) working group is to help resolve the confusion among the different systems of rating evidence and recommendations. The group has wide representation from many organizations, including the Agency …

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References

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Schunemann HJ, Best D, Vist G, Oxman AD. Letters, numbers, symbols and words: how to communicate grades of evidence and recommendations. CMAJ. 2003;169:677-80. [PMID: 14517128]
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Atkins D, Best D, Briss PA, et al. Grading quality of evidence and strength of recommendations. BMJ. 2004;328:1490. [PMID: 15205295]
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Guyatt GG, Bauman M, Adrizzo-Harris D, et al. Grading strength of recommendations and quality of evidence in clinical guidelines. Chest. 2005. In press.
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Devereaux PJ, Choi PT, Lacchetti C, et al. A systematic review and meta-analysis of studies comparing mortality rates of private for-profit and private not-for-profit hospitals. CMAJ. 2002;166:1399-406. [PMID: 12054406]
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Charles C, Whelan T, Gafni A. What do we mean by partnership in making decisions about treatment? BMJ. 1999;319:780-2. [PMID: 10488014]
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CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). Lancet. 1996;348:1329-39. [PMID: 8918275]

Information & Authors

Information

Published In

cover image ACP Journal Club
ACP Journal Club
Volume 144Number 1January 1, 2006
Pages: A8
Editors: Gordon Guyatt, MSc, MD, McMaster University, Hamilton, Ontario, Canada (G.G.), Gunn Vist, PhD, Norwegian Knowledge Centre for the Health Services, Oslo, Norway (G.V.), Yngve Falck-Ytter, MD, Case Western Reserve University, Cleveland, Ohio, USA (Y.F.), Regina Kunz, MD, MSc, PhD, Institute for Clinical Epidemiology, Basel, Switzerland (R.K.), Nicola Magrini, MD, Centre for Evaluation of the Effectiveness of Health Care, Modena, Italy (N.M.), and Holger Schunemann, MD, PhD, McMaster University and Italian National Cancer Institute Regina Elena, Hamilton, Ontario, Canada and Rome, Italy (H.S.)

History

Published in issue: January 1, 2006
Published online: 9 March 2020

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