Evidence-based medicine
An internist sees a 70-year-old man whose main problem is fatigue. The initial investigation reveals a hemoglobin of 90 g/L. The internist suspects iron deficiency anemia. How might she proceed?
When faced with this situation during her training just a few years earlier, the internist was told by the attending physician that one ordered serum ferritin and transferrin saturation and proceeded according to the results. She now follows this path. If both results come back below the laboratory's lower limit of normal, she will make a diagnosis of iron deficiency anemia, and investigate and treat accordingly. If both results are …
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References
1.
Guyatt GH, Patterson C, Ali M, et al. Diagnosis of iron-deficiency anemia in the elderly. Am J Med. 1990;88:205-9.
2.
Sackett DL, Haynes RB, Guyatt GH, Tugwell P. Clinical Epidemiology, a Basic Science for Clinical Medicine. 2nd ed. Boston: Little, Brown and Company. [In press for 1991].
3.
Guyatt GH, Keller JL, Jaeschke R, et al. The n-of-1 randomized controlled trial: clinical usefulness. Our three-year experience. Ann Intern Med. 1990;112:293-9.
Information & Authors
Information
Published In
ACP Journal Club
Volume 114 • Number 2 • March 1, 1991
Pages: A16
Editor: Gordon H. Guyatt, MD, MSc
History
Published in issue: March 1, 1991
Published online: 9 March 2020
Copyright
© 1991 American College of Physicians.
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