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6 April 2021

Joint testing of IgM and IgG has high value for ruling in SARS-CoV-2 infection

Author: Mark Loeb, MD, MScAuthor, Article, & Disclosure Information
Publication: Annals of Internal Medicine
Volume 174, Number 4
https://doi.org/10.7326/ACPJ202104200-047
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Abstract

Source Citation

Guo CC, Mi JQ, Nie H. Seropositivity rate and diagnostic accuracy of serological tests in 2019-nCoV cases: a pooled analysis of individual studies. Eur Rev Med Pharmacol Sci. 2020;24:10208-18. https://pubmed.ncbi.nlm.nih.gov/33090430/

Abstract

Clinical Impact Ratings

GIM/FP/GP: 6 out of 7
Emergency Med: 5 out of 7
Hospitalists: 5 out of 7
Infectious Disease: 5 out of 7
Public Health: 6 out of 7

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References

1.
Cheng MP, Papenburg J, Desjardins M, et al. Diagnostic testing for severe acute respiratory syndrome-related coronavirus 2: a narrative review. Ann Intern Med. 2020;172:726-34. [PMID: 32282894]
PubMed
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2.
Hanson KE, Caliendo AM, Arias CA, et al. Infectious Diseases Society of America guidelines on the diagnosis of COVID-19: serologic testing. Clin Infect Dis. 2020. [Epub ahead of print]. [PMID: 32918466]
PubMed
Google Scholar

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Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 174 • Number 4 • April 2021
Pages: JC47

History

Published online: 6 April 2021
Published in issue: April 2021

Keywords

  1. Antibodies
  2. COVID-19
  3. Disclosure
  4. Enzyme immunoassay
  5. Enzyme linked immunosorbent assay
  6. Immunoassays
  7. Prevention, policy, and public health
  8. Reverse transcriptase polymerase chain reaction
  9. RNA
  10. Specificity

Copyright

© 2021 American College of Physicians.

Authors

Affiliations

Mark Loeb, MD, MSc
McMaster University, Hamilton, Ontario, Canada (M.L.)
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This article was published at Annals.org on 6 April 2021.

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Mark Loeb. Joint testing of IgM and IgG has high value for ruling in SARS-CoV-2 infection. Ann Intern Med.2021;174:JC47. [Epub 6 April 2021]. doi:10.7326/ACPJ202104200-047

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