ACP Journal Club
15 December 2020

In patients at high CV risk receiving simvastatin, the Myopathy Risk Score predicted statin-related myopathy

Publication: Annals of Internal Medicine
Volume 173, Number 12

Abstract

Source Citation

Hopewell JC, Offer A, Haynes R, et al. Independent risk factors for simvastatin-related myopathy and relevance to different types of muscle symptom. Eur Heart J. 2020;41:3336-42. https://pubmed.ncbi.nlm.nih.gov/32702748/

Abstract

Clinical Impact Ratings

GIM/FP/GP: 6 out of 7
Cardiology: 5 out of 7

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Reference

1.
Wiggins BS, Saseen JJ, Page RL 2nd, et al. Recommendations for management of clinically significant drug–drug interactions with statins and select agents used in patients with cardiovascular disease: a scientific statement from the American Heart Association. Circulation. 2016;134:e468-95. [PMID: 27754879]

Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 173Number 1215 December 2020
Pages: JC71

History

Published online: 15 December 2020
Published in issue: 15 December 2020

Keywords

Authors

Affiliations

Michelle D. Kelsey, MD
Duke University, Durham, North Carolina, USA (M.D.K., L.K.N.)
L. Kristin Newby, MD, MHS
Duke University, Durham, North Carolina, USA (M.D.K., L.K.N.)
Disclosures: The commentators have disclosed no conflicts of interest. The forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M19-3050.

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Michelle D. Kelsey, L. Kristin Newby. In patients at high CV risk receiving simvastatin, the Myopathy Risk Score predicted statin-related myopathy. Ann Intern Med.2020;173:JC71. [Epub 15 December 2020]. doi:10.7326/ACPJ202012150-071

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