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ACP Journal Club
16 April 2013

Adding renal dysfunction to CHADS2 did not improve prediction of stroke or systemic embolism in AF

Authors: Catherine M. Clase, MD, Deborah L. Zimmerman, MD, and Benjamin K. A. Thomson, MDAuthor, Article, & Disclosure Information
Publication: Annals of Internal Medicine
Volume 158, Number 8
https://doi.org/10.7326/0003-4819-158-8-201304160-02013
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Abstract

Source Citation

Piccini JP, Stevens SR, Chang Y, et al. Renal dysfunction as a predictor of stroke and systemic embolism in patients with nonvalvular atrial fibrillation: validation of the R2CHADS2 index in the ROCKET and ATRIA study cohorts. Circulation. 2013;127:224-32. https://pubmed.ncbi.nlm.nih.gov/23212720/

Abstract

Clinical Impact Ratings

Cardiology: 6 out of 7
Nephrology: 6 out of 7
Neurology: 6 out of 7

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References

1.
Olesen JB, Lip GY, Kamper AL, et al. Stroke and bleeding in atrial fibrillation with chronic kidney disease. N Engl J Med. 2012;367:625-35. [PMID: 22894575]
PubMed
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2.
Limdi NA, Beasley TM, Baird MF, et al. Kidney function influences warfarin responsiveness and hemorrhagic complications. J Am Soc Nephrol. 2009;20:912-21. [PMID: 19225037]
PubMed
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Information & Authors

Information

Published In

cover image Annals of Internal Medicine
Annals of Internal Medicine
Volume 158 • Number 8 • 16 April 2013
Pages: JC13

History

Published online: 16 April 2013
Published in issue: 16 April 2013

Keywords

  1. Atrial fibrillation
  2. Cohort studies
  3. Creatinine
  4. Heart failure
  5. Hypertension
  6. Ischemic stroke
  7. Medical risk factors
  8. Randomized trials
  9. Stroke
  10. Transient ischemic attacks

Copyright

© 2013 American College of Physicians.

Authors

Affiliations

Catherine M. Clase, MD
McMaster University, Hamilton, Ontario, Canada (C.M.C.)
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Deborah L. Zimmerman, MD
University of Ottawa, Ottawa, Ontario, Canada (D.L.Z.)
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Benjamin K. A. Thomson, MD
Western University, London, Ontario, Canada (B.K.A.)
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This article was published at Annals.org on 2 April 2013.

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Catherine M. Clase, Deborah L. Zimmerman, Benjamin K. A. Thomson. Adding renal dysfunction to CHADS2 did not improve prediction of stroke or systemic embolism in AF. Ann Intern Med.2013;158:JC13. [Epub 16 April 2013]. doi:10.7326/0003-4819-158-8-201304160-02013

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