The prevalence of obesity is increasing worldwide, with serious consequences for affected individuals, health care systems, and society. Because of the lack of effective interventions for obesity prevention, obesity is likely to continue to be a major public health challenge for many years to come. Once obesity occurs, the available medical treatment options include only a diminishing array of drugs and bariatric surgery. The key to successful weight loss and its maintenance is adoption of a healthy lifestyle through altering food selection, reducing calorie intake, and increasing physical activity (1). Unfortunately, many obese individuals do not successfully modify their lifestyle, ...
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Author, Article, and Disclosure Information
From University of Birmingham, Birmingham Collaboration for Leadership in Health Research and Care, and Heartlands Biomedical Research Centre, Birmingham B9 5SS, United Kingdom; and Stanford Sleep Medicine Center, Redwood City, CA 94063.
Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-2045.
Corresponding Author: Shahrad Taheri, MBBS, PhD, Heartlands Biomedical Research Centre, MIDRU Building, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, United Kingdom; e-mail, S.
Current Author Addresses: Dr. Taheri: Heartlands Biomedical Research Centre, MIDRU Building, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, United Kingdom.
Dr. Mignot: Stanford Sleep Medicine Center, 450 Broadway Street, Pavilion B, 2nd Floor, Redwood City, CA 94063.