Letters15 April 2008
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    Background: A subset of patients with Clostridium difficile–associated diarrhea will develop fulminant, life-threatening C. difficile infection that is refractory to medical therapy. Surgical options for fulminant disease are associated with high mortality rates. We describe a patient with fulminant C. difficile infection successfully treated with donor stool by retention enema.

    Objective: To describe a successful case of using fecal bacteriotherapy to treat life-threatening, fulminant C. difficile enterocolitis.

    Case Report: A 69-year-old man was admitted to the hospital after undergoing radical prostatectomy. The patient was given perioperative, intravenous cefazolin. On postoperative day 2, the patient developed an ileus and oliguric renal ...


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