Articles18 April 2006
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    Abstract

    Background:

    In western populations, coffee consumption is associated with a reduced risk for type 2 diabetes; however, the effect of green, black, and oolong teas is unclear.

    Objective:

    To examine the relationship between consumption of these beverages and risk for diabetes.

    Design:

    Retrospective cohort study.

    Setting:

    25 communities across Japan.

    Participants:

    A total of 17 413 persons (6727 men and 10 686 women; 49% of the original study population) who were 40 to 65 years of age; had no history of type 2 diabetes, cardiovascular disease, or cancer at the baseline lifestyle survey; and completed the 5-year follow-up questionnaire. There was no difference in body mass index levels at baseline between respondents and nonrespondents.

    Measurements:

    Questionnaire on consumption of coffee; black, green, and oolong teas; and physician-diagnosed diabetes.

    Results:

    During the 5-year follow-up, there were 444 self-reported new cases of diabetes in 231 men and 213 women (5-year event rates, 3.4% and 2.0%, respectively). Consumption of green tea and coffee was inversely associated with risk for diabetes after adjustment for age, sex, body mass index, and other risk factors. Multivariable odds ratios for diabetes among participants who frequently drank green tea and coffee (≥6 cups of green tea per day and ≥3 cups of coffee per day) were 0.67 (95% CI, 0.47 to 0.94) and 0.58 (CI, 0.37 to 0.90), respectively, compared with those who drank less than 1 cup per week. No association was found between consumption of black or oolong teas and the risk for diabetes. Total caffeine intake from these beverages was associated with a 33% reduced risk for diabetes. These inverse associations were more pronounced in women and in overweight men.

    Limitations:

    Diabetes was self-reported, no data were available on consumption of soda, and the follow-up rate was low.

    Conclusions:

    Consumption of green tea, coffee, and total caffeine was associated with a reduced risk for type 2 diabetes.

    *For members of the JACC Study Group, see the Appendix.

    References

    • 1. King HAubert REHerman WHGlobal burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care1998;21:1414-31. [PMID: 9727886] CrossrefMedlineGoogle Scholar
    • 2. Ohmura TUeda KKiyohara YKato IIwamoto HNakayama Ket alPrevalence of type 2 (non–insulin-dependent) diabetes mellitus and impaired glucose tolerance in the Japanese general population: the Hisayama Study. Diabetologia1993;36:1198-203. [PMID: 8270136] CrossrefMedlineGoogle Scholar
    • 3. van Dam RMFeskens EJCoffee consumption and risk of type 2 diabetes mellitus. Lancet2002;360:1477-8. [PMID: 12433517] CrossrefMedlineGoogle Scholar
    • 4. Rosengren ADotevall AWilhelmsen LThelle DJohansson SCoffee and incidence of diabetes in Swedish women: a prospective 18-year follow-up study. J Intern Med2004;255:89-95. [PMID: 14687243] CrossrefMedlineGoogle Scholar
    • 5. Tuomilehto JHu GBidel SLindstrom JJousilahti PCoffee consumption and risk of type 2 diabetes mellitus among middle-aged Finnish men and women. JAMA2004;291:1213-9. [PMID: 15010442] CrossrefMedlineGoogle Scholar
    • 6. Salazar-Martinez EWillett WCAscherio AManson JELeitzmann MFStampfer MJet alCoffee consumption and risk for type 2 diabetes mellitus. Ann Intern Med2004;140:1-8. [PMID: 14706966] LinkGoogle Scholar
    • 7. Carlsson SHammar NGrill VKaprio JCoffee consumption and risk of type 2 diabetes in Finnish twins [Letter]. Int J Epidemiol2004;33:616-7. [PMID: 15105411] CrossrefMedlineGoogle Scholar
    • 8. Sasazuki SInoue MHanaoka TYamamoto SSobue TTsugane SGreen tea consumption and subsequent risk of gastric cancer by subsite: the JPHC Study. Cancer Causes Control2004;15:483-91. [PMID: 15286468] CrossrefMedlineGoogle Scholar
    • 9. Ohno YTamakoshi AJACC Study GroupJapan collaborative cohort study for evaluation of cancer risk sponsored by Monbusho (JACC study). J Epidemiol2001;11:144-50. [PMID: 11512570] CrossrefMedlineGoogle Scholar
    • 10. Date CFukui MYamamoto AWakai KOzeki AMotohashi Yet alReproducibility and validity of a self-administered food frequency questionnaire used in the JACC study. J Epidemiol2005;15 Suppl 1 S9-23. [PMID: 15881192] CrossrefMedlineGoogle Scholar
    • 11. The Resource Council of the Science and Technology Agency of JapanStandard Tables of Food Composition in Japan. 5th ed, revised. Tokyo: Printing Bureau, Ministry of Finance; 2000. Google Scholar
    • 12. The Expert Committee on the Diagnosis and Classification of Diabetes MellitusReport of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care1997;20:1183-197. [PMID: 12502614] CrossrefMedlineGoogle Scholar
    • 13. Salmeron JManson JEStampfer MJColditz GAWing ALWillett WCDietary fiber, glycemic load, and risk of non–insulin-dependent diabetes mellitus in women. JAMA1997;277:472-7. [PMID: 9020271] CrossrefMedlineGoogle Scholar
    • 14. Kao WHFolsom ARNieto FJMo JPWatson RLBrancati FLSerum and dietary magnesium and the risk for type 2 diabetes mellitus: the Atherosclerosis Risk in Communities Study. Arch Intern Med1999;159:2151-9. [PMID: 10527292] CrossrefMedlineGoogle Scholar
    • 15. Astrup AToubro SCannon SHein PBreum LMadsen JCaffeine: a double-blind, placebo-controlled study of its thermogenic, metabolic, and cardiovascular effects in healthy volunteers. Am J Clin Nutr1990;51:759-67. [PMID: 2333832] CrossrefMedlineGoogle Scholar
    • 16. Spriet LLMacLean DADyck DJHultman ECederblad GGraham TECaffeine ingestion and muscle metabolism during prolonged exercise in humans. Am J Physiol1992;262:891-8. [PMID: 1616022] MedlineGoogle Scholar
    • 17. Keijzers GBDe Galan BETack CJSmits PCaffeine can decrease insulin sensitivity in humans. Diabetes Care2002;25:364-9. [PMID: 11815511] CrossrefMedlineGoogle Scholar
    • 18. Robertson DWade DWorkman RWoosley RLOates JATolerance to the humoral and hemodynamic effects of caffeine in man. J Clin Invest1981;67:1111-7. [PMID: 7009653] CrossrefMedlineGoogle Scholar
    • 19. Waltner-Law MEWang XLLaw BKHall RKNawano MGranner DKEpigallocatechin gallate, a constituent of green tea, represses hepatic glucose production. J Biol Chem2002;277:34933-40. [PMID: 12118006] CrossrefMedlineGoogle Scholar
    • 20. Song EKHur HHan MKEpigallocatechin gallate prevents autoimmune diabetes induced by multiple low doses of streptozotocin in mice. Arch Pharm Res2003;26:559-63. [PMID: 12934649] CrossrefMedlineGoogle Scholar
    • 21. Devasagayam TPKamat JPMohan HKesavan PCCaffeine as an antioxidant: inhibition of lipid peroxidation induced by reactive oxygen species. Biochim Biophys Acta1996;1282:63-70. [PMID: 8679661] CrossrefMedlineGoogle Scholar
    • 22. Hemmerle HBurger HJBelow PSchubert GRippel RSchindler PWet alChlorogenic acid and synthetic chlorogenic acid derivatives: novel inhibitors of hepatic glucose-6-phosphate translocase. J Med Chem1997;40:137-45. [PMID: 9003513] CrossrefMedlineGoogle Scholar