The presentation of the study by Rauramaa and colleagues (1) was grossly misleading. The abstract stated that “aerobic physical exercise did not attenuate progression of atherosclerosis, except in a subgroup of men not taking statins,” a conclusion echoed by the Editors' Notes and the Summary for Patients (2). This appeared to be a truly negative study, one that could lead physicians and patients to take their statin and forget about exercise.

Well, surprise: Only 15 of the 140 enrollees were taking statins, and among the 125 who weren't, progression of atherosclerosis was 40% less in the exercise ...


  • 1. Rauramaa RHalonen PVäisänen SBLakka TASchmidt-Trucksäss ABerg Aet alEffects of aerobic physical exercise on inflammation and atherosclerosis in men: the DNASCO Study: a six-year randomized, controlled trial. Ann Intern Med2004;140:1007-14. [PMID: 15197018] LinkGoogle Scholar
  • 2. Summaries for patients. Does aerobic exercise slow progression of atherosclerosis? Ann Intern Med2004;140:I37. [PMID: 15197036] LinkGoogle Scholar